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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WEE1
All Species:
16.97
Human Site:
S85
Identified Species:
28.72
UniProt:
P30291
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30291
NP_003381.1
646
71597
S85
S
P
G
P
A
P
G
S
P
G
E
L
E
E
D
Chimpanzee
Pan troglodytes
XP_521839
646
71607
S85
S
P
G
P
T
P
G
S
P
G
E
L
E
E
D
Rhesus Macaque
Macaca mulatta
NP_001099016
568
63102
G53
V
Q
D
S
E
A
K
G
T
P
P
W
T
P
L
Dog
Lupus familis
XP_534051
887
95991
S326
S
P
G
P
A
P
G
S
P
G
E
L
E
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P47810
646
71560
S85
S
P
G
A
E
P
S
S
P
G
E
L
E
D
D
Rat
Rattus norvegicus
Q63802
646
71478
S85
S
P
G
A
E
P
S
S
P
G
E
L
E
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510171
572
63943
P57
P
G
H
F
A
N
F
P
V
M
W
M
E
K
I
Chicken
Gallus gallus
NP_001026352
641
70947
P92
E
E
E
E
M
M
E
P
A
A
A
P
L
P
D
Frog
Xenopus laevis
P47817
555
61670
P39
E
G
P
Q
K
G
S
P
V
S
S
W
R
T
N
Zebra Danio
Brachydanio rerio
NP_001005770
612
68517
E85
D
D
E
S
W
D
E
E
G
F
G
S
P
S
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54350
609
68790
S85
E
G
G
D
G
D
V
S
M
S
P
P
C
Q
K
Honey Bee
Apis mellifera
XP_624069
589
66032
N74
N
N
Q
S
V
P
I
N
N
N
K
T
P
I
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999796
624
68925
L85
N
V
D
P
N
S
R
L
H
D
G
E
N
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L4H0
500
56512
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
42.1
70.9
N.A.
90.5
91.6
N.A.
72.7
80.1
42.8
64.2
N.A.
36.5
41.6
N.A.
39.6
Protein Similarity:
100
99.8
56.1
71.3
N.A.
92.7
93.1
N.A.
79.2
85.9
55.2
75
N.A.
54.1
59.2
N.A.
55.5
P-Site Identity:
100
93.3
0
100
N.A.
73.3
80
N.A.
13.3
6.6
0
0
N.A.
13.3
6.6
N.A.
6.6
P-Site Similarity:
100
93.3
0
100
N.A.
80
80
N.A.
26.6
6.6
6.6
0
N.A.
20
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
22
8
0
0
8
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
8
15
8
0
15
0
0
0
8
0
0
0
8
43
% D
% Glu:
22
8
15
8
22
0
15
8
0
0
36
8
43
29
0
% E
% Phe:
0
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% F
% Gly:
0
22
43
0
8
8
22
8
8
36
15
0
0
0
0
% G
% His:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
15
% I
% Lys:
0
0
0
0
8
0
8
0
0
0
8
0
0
8
8
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
0
36
8
0
8
% L
% Met:
0
0
0
0
8
8
0
0
8
8
0
8
0
0
0
% M
% Asn:
15
8
0
0
8
8
0
8
8
8
0
0
8
0
8
% N
% Pro:
8
36
8
29
0
43
0
22
36
8
15
15
15
15
0
% P
% Gln:
0
8
8
8
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
8
% R
% Ser:
36
0
0
22
0
8
22
43
0
15
8
8
0
15
8
% S
% Thr:
0
0
0
0
8
0
0
0
8
0
0
8
8
8
0
% T
% Val:
8
8
0
0
8
0
8
0
15
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
8
15
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _